Journal of Renal Cancer

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Table of Content: Volume 4, Issue 1

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Research Article Pages 41-49

Single-Cell RNA Sequencing Identifies SLC6A3 as a Biomarker and Prognostic Marker in Clear Cell Renal Cell Carcinoma

Authors: Sathiya Pandi Narayanan, Ramani Gopal, Sebastian Arockia Jenifer and Tariq Ahmad Masoodi

Abstract: The SLC6A3 gene encodes dopamine protein and is a member of the sodium and chloride-dependent neurotransmitter transporter family. While the role of SLC6A3 in Parkinson's disease is well established, its function in cancer, especially in clear cell renal cell carcinoma (ccRCC), remains unclear.

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Research Article Pages 34-40

Characteristics Associated with Outcomes of Small Renal Mass Thermal Ablation

Authors: Vincent Galate, BA, Zachary Nicek, MD, Carissa Walter, MPH, Xiaosong Shi, MS, Yanming Li, PhD, Kate Young, MS, Lauren Clark, MS, Aaron Rohr, MS, MD and Zachary Collins, MD

Abstract: This single-center retrospective cohort study included patients age 18 and older who underwent CT-guided percutaneous renal tumor MWA or cryoablation for primary renal malignancy between 3/1/2010 and 1/31/2021 with at least two years of contrast-enhanced cross-sectional imaging follow-up. Patient demographics, procedure details, pre- and post-procedure imaging, and tumor characteristics were collected. Negative outcome was defined as recurrent or residual tumor nodularity at the treated tumor site. Categorical characteristics and event status were analyzed using Chi Square and Fisher's exact tests. Kaplan Meier curves were used to analyze event-free survival.

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